Z-Guggulsterone is a major ingredient in the Indian traditional hypolipidemic remedy guggul.A study in mice has established that its hypolipidemic effect involves the farnesoid X receptor (FXR), presumably by acting as an antagonist of this receptor.It is generally assumed that the antagonism leads to induction of cytochrome P450 7A1 (CYP7A1), the
This paper elucidates the challenges and opportunities inherent in integrating data-driven Freezer Basket Front methodologies into geotechnics, drawing inspiration from the success of materials informatics.Highlighting the intricacies of soil complexity, heterogeneity, and the lack of comprehensive data, the discussion underscores the pressing need
The Harappan Civilization occupies a unique place among the early civilizations of the world with its well planned urban settlements, advanced handicraft and technology, religious and trade activities.Using a Geographical Information Systems (GIS), this study presents spatial analyses that locate urban settlements on a digital elevation model (DEM)
Generalized differential transform method (GDTM) is a powerful method to solve the Shorts fractional differential equations.In this paper, a new fractional model for systems with single degree of freedom (SDOF) is presented, by using the GDTM.The advantage of this method compared with some other numerical methods has been shown.The analysis of new